专利名称:SOLUTION FOR PRESERVING VASCULAR
CONDUITS
发明人:SURYAN, MAHENDRA,MENON, SATISH申请号:EP13868525申请日:20131227公开号:EP2938187A4公开日:20160810
摘要:Organ and tissue preservation formulations with improved stability shelf life areprovided by separating the formulation into a first solution having a pH of at least 7 anda second solution having a pH of less than 7. The first solution includes components withimproved stability when stored at a pH of 7 or above, and the second solution includescomponents with improved stability when stored at a pH below 7. The first solutionincludes water, a balanced salt solution, a sugar, adenosine, orotic acid, malic acid, L-carnitine, and insulin. The second solution includes water, an antioxidant such as ascorbicacid, a cellular reducing agent such as reduced glutathione, L-citrulline, creatine
monohydrate, L-carnosine, and L-arginine. During use, the first and second solutions aremixed to form a formulation final formulation that can be used at a physiological pH topreserve the function of the tissue or organ.
申请人:SOMAHLUTION, LLC
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